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Anti-Human AIMP2 Polyclonal Antibody (ARO-A12574)

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概述
货号ARO-A12574
品牌ProteoGenix
描述
Anti-Human AIMP2 Polyclonal Antibody (ARO-A12574) is a rabbit polyclonal antibody detecting Protein JTV-1, Multisynthase complex auxiliary component p38, AIMP2, JTV1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Cricetulus griseus.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Cricetulus griseus
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human AIMP2 (Lys120-Lys320).
靶标Protein JTV-1, Multisynthase complex auxiliary component p38, AIMP2, JTV1, Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
纯化方式Purified by antigen affinity column.
Accession号Q13155
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (AIMP2) is a ~35 kDa protein. Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.

1. Kaminska, M. et al. (2009) The Journal of biological chemistry 284, 6053-60. PMID: 19131329
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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