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Anti-Human TLE3 Polyclonal Antibody (ARO-A12554)

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概述
货号ARO-A12554
品牌ProteoGenix
描述
Anti-Human TLE3 Polyclonal Antibody (ARO-A12554) is a rabbit polyclonal antibody detecting Transducin-like enhancer protein 3, KIAA1547, TLE3, Enhancer of split groucho-like protein 3, ESG3 in ELISA, IHC, WB. Suitable for Danio rerio, Drosophila melanogaster, Human, Mouse, Rat, Xenopus laevis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Danio rerio, Drosophila melanogaster, Human, Mouse, Rat, Xenopus laevis
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human TLE3 (Ser449-Tyr772).
靶标Transducin-like enhancer protein 3, KIAA1547, TLE3, Enhancer of split groucho-like protein 3, ESG3
纯化方式Purified by antigen affinity column.
Accession号Q04726
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Transducin-like enhancer protein 3 (TLE3) is a ~83 kDa protein. Transcriptional coregulator that binds to a number of transcription factors. Acts as a regulator of adipogenesis both by acting as a corepressor of Wnt signaling and coactivator for PPARG. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. Promotes diffentiation of white adipocytes by acting as a coactivator for PPARG and preventing the association between PRDM16 and PPARG, thereby preventing browning of white adipocytes.

1. Flack, JE. et al. (2017) Molecular cell 67, 181-193.e5. PMID: 28689657
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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