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Anti-Human IFIT2 Polyclonal Antibody (ARO-A12605)

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概述
货号ARO-A12605
品牌ProteoGenix
描述
Anti-Human IFIT2 Polyclonal Antibody (ARO-A12605) is a rabbit polyclonal antibody detecting P54, Interferon-induced 54 kDa protein, Interferon-induced protein with tetratricopeptide repeats 2, CIG-42, G10P2, IFI54, IFIT-2, IFI-54K, ISG-54 K, IFIT2, ISG54 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human IFIT2 (Met1-Glu472).
靶标P54, Interferon-induced 54 kDa protein, Interferon-induced protein with tetratricopeptide repeats 2, CIG-42, G10P2, IFI54, IFIT-2, IFI-54K, ISG-54 K, IFIT2, ISG54
纯化方式Purified by antigen affinity column.
Accession号P09913
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interferon-induced protein with tetratricopeptide repeats 2 (IFIT2) is a ~54 kDa protein. IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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