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Anti-Human CLPP Polyclonal Antibody (ARO-A12589)

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概述
货号ARO-A12589
品牌ProteoGenix
描述
Anti-Human CLPP Polyclonal Antibody (ARO-A12589) is a rabbit polyclonal antibody detecting Endopeptidase Clp, ATP-dependent Clp protease proteolytic subunit, mitochondrial, CLPP in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Bos taurus
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CLPP (Gly21-His247).
靶标Endopeptidase Clp, ATP-dependent Clp protease proteolytic subunit, mitochondrial, CLPP
纯化方式Purified by antigen affinity column.
Accession号Q16740
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-dependent Clp protease proteolytic subunit, mitochondrial (CLPP) is a ~30 kDa protein. Protease component of the ClpXP complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The ClpXP complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates. Cleaves PINK1 in the mitochondrion.

1. Kang, SG. et al. (2002) The Journal of biological chemistry 277, 21095-102. PMID: 11923310
2. Kang, SG. et al. (2004) Journal of structural biology 148, 338-52. PMID: 15522782
3. Greene, AW. et al. (2012) EMBO reports 13, 378-85. PMID: 22354088
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human CLPP Polyclonal Antibody

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