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Anti-Human STEAP4 Polyclonal Antibody (ARO-A12543)

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概述
货号ARO-A12543
品牌ProteoGenix
描述
Anti-Human STEAP4 Polyclonal Antibody (ARO-A12543) is a rabbit polyclonal antibody detecting STEAP4, STAMP2, Tumor necrosis factor, alpha-induced protein 9, Metalloreductase STEAP4, TNFAIP9, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human STEAP4 (Thr21-Gln195).
靶标STEAP4, STAMP2, Tumor necrosis factor, alpha-induced protein 9, Metalloreductase STEAP4, TNFAIP9, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2
纯化方式Purified by antigen affinity column.
Accession号Q687X5
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Metalloreductase STEAP4 is a ~51 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance.

1. Oosterheert, W. et al. (2018) Nature communications 9, 4337. PMID: 30337524
2. Arner, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 2249-54. PMID: 18381574
3. Zhang, CM. et al. (2008) Acta pharmacologica Sinica 29, 587-92. PMID: 18430367
4. Inoue, A. et al. (2009) Arthritis research & therapy 11, R118. PMID: 19660107
5. Tamura, T. et al. (2009) International journal of molecular medicine 24, 599-604. PMID: 19787193
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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