

| 货号 | ARO-A12543 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human STEAP4 Polyclonal Antibody (ARO-A12543) is a rabbit polyclonal antibody detecting STEAP4, STAMP2, Tumor necrosis factor, alpha-induced protein 9, Metalloreductase STEAP4, TNFAIP9, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human STEAP4 (Thr21-Gln195). |
| 靶标 | STEAP4, STAMP2, Tumor necrosis factor, alpha-induced protein 9, Metalloreductase STEAP4, TNFAIP9, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q687X5 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Metalloreductase STEAP4 is a ~51 kDa protein. Integral membrane protein that functions as a NADPH-dependent ferric-chelate reductase, using NADPH from one side of the membrane to reduce a Fe(3+) chelate that is bound on the other side of the membrane. Mediates sequential transmembrane electron transfer from NADPH to FAD and onto heme, and finally to the Fe(3+) chelate. Can also reduce Cu(2+) to Cu(1+). Plays a role in systemic metabolic homeostasis, integrating inflammatory and metabolic responses. Associated with obesity and insulin-resistance. 1. Oosterheert, W. et al. (2018) Nature communications 9, 4337. PMID: 30337524 2. Arner, P. et al. (2008) The Journal of clinical endocrinology and metabolism 93, 2249-54. PMID: 18381574 3. Zhang, CM. et al. (2008) Acta pharmacologica Sinica 29, 587-92. PMID: 18430367 4. Inoue, A. et al. (2009) Arthritis research & therapy 11, R118. PMID: 19660107 5. Tamura, T. et al. (2009) International journal of molecular medicine 24, 599-604. PMID: 19787193 |
| Note | For research use only. |

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