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Anti-Human IMMT Polyclonal Antibody (ARO-A12632)

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概述
货号ARO-A12632
品牌ProteoGenix
描述
Anti-Human IMMT Polyclonal Antibody (ARO-A12632) is a rabbit polyclonal antibody detecting p87/89, Mitofilin, Mitochondrial inner membrane protein, IMMT, HMP, MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, MIC60, MINOS2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human IMMT (Ala489-Glu758).
靶标p87/89, Mitofilin, Mitochondrial inner membrane protein, IMMT, HMP, MICOS complex subunit MIC60, Cell proliferation-inducing gene 4/52 protein, MIC60, MINOS2
纯化方式Purified by antigen affinity column.
Accession号Q16891
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

MICOS complex subunit MIC60 (IMMT) is a ~83 kDa protein. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology.

1. Alkhaja, AK. et al. (2012) Molecular biology of the cell 23, 247-57. PMID: 22114354
2. Ott, C. et al. (2015) PloS one 10, e0120213. PMID: 25781180
3. Stephan, T. et al. (2020) The EMBO journal 39, e104105. PMID: 32567732
4. Hu, C. et al. (2020) Cell death & disease 11, 940. PMID: 33130824
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-Human IMMT Polyclonal Antibody

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