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Anti-Human GABARAPL2 Polyclonal Antibody (ARO-A12698)

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概述
货号ARO-A12698
品牌ProteoGenix
描述
Anti-Human GABARAPL2 Polyclonal Antibody (ARO-A12698) is a rabbit polyclonal antibody detecting MAP1 light chain 3-related protein, GABA(A) receptor-associated protein-like 2, General protein transport factor p16, Ganglioside expression factor 2, GATE-16, GEF-2, GABARAPL2, Golgi-associated ATPase enhancer of 16 kDa, Gamma-aminobutyric acid receptor-associated protein-like 2, FLC3A, GEF2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human GABARAPL2 (Met1-Phe117).
靶标MAP1 light chain 3-related protein, GABA(A) receptor-associated protein-like 2, General protein transport factor p16, Ganglioside expression factor 2, GATE-16, GEF-2, GABARAPL2, Golgi-associated ATPase enhancer of 16 kDa, Gamma-aminobutyric acid receptor-associated protein-like 2, FLC3A, GEF2
纯化方式Purified by antigen affinity column.
Accession号P60520
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Gamma-aminobutyric acid receptor-associated protein-like 2 (GABARAPL2) is a ~13 kDa protein. Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production.

1. Weidberg, H. et al. (2010) The EMBO journal 29, 1792-802. PMID: 20418806
2. Zhu, Y. et al. (2013) The Journal of biological chemistry 288, 1099-113. PMID: 23209295
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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