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Anti-NOSIP Polyclonal Antibody (ARO-A13581)

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概述
货号ARO-A13581
品牌ProteoGenix
描述
Anti-NOSIP Polyclonal Antibody (ARO-A13581) is a rabbit polyclonal antibody detecting eNOS-interacting protein, NOSIP, RING-type E3 ubiquitin transferase NOSIP, Nitric oxide synthase-interacting protein, E3 ubiquitin-protein ligase NOSIP in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus, Macaca fascicularis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Bos taurus, Macaca fascicularis
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human NOSIP (Gly62-Ser295).
靶标eNOS-interacting protein, NOSIP, RING-type E3 ubiquitin transferase NOSIP, Nitric oxide synthase-interacting protein, E3 ubiquitin-protein ligase NOSIP
纯化方式Purified by antigen affinity column.
Accession号Q9Y314
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Nitric oxide synthase-interacting protein (NOSIP) is a ~33 kDa protein. E3 ubiquitin-protein ligase that is essential for proper development of the forebrain, the eye, and the face. Catalyzes monoubiquitination of serine/threonine-protein phosphatase 2A (PP2A) catalytic subunit PPP2CA/PPP2CB. Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity.

1. Dedio, J. et al. (2001) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 15, 79-89. PMID: 11149895
2. Dreyer, J. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 10454-65. PMID: 15548660
3. Schleicher, M. et al. (2005) Molecular and cellular biology 25, 8251-8. PMID: 16135813
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-NOSIP Polyclonal Antibody

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