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Anti-CLIC4 Polyclonal Antibody (ARO-A13569)

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概述
货号ARO-A13569
品牌ProteoGenix
描述
Anti-CLIC4 Polyclonal Antibody (ARO-A13569) is a rabbit polyclonal antibody detecting Chloride intracellular channel protein 4, CLIC4, Intracellular chloride ion channel protein p64H1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CLIC4 (Met1-Lys253).
靶标Chloride intracellular channel protein 4, CLIC4, Intracellular chloride ion channel protein p64H1
纯化方式Purified by antigen affinity column.
Accession号Q9Y696
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Chloride intracellular channel protein 4 (CLIC4) is a ~28 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis. Could also promote endothelial cell proliferation and regulate endothelial morphogenesis (tubulogenesis).

1. Al Khamici, H. et al. (2015) PloS one 10, e115699. PMID: 25581026
2. Alghalayini, A. et al. (2023) Biomolecules 13. PMID: 37759794
3. Littler, DR. et al. (2005) The FEBS journal 272, 4996-5007. PMID: 16176272
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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