

| 货号 | ARO-A13590 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-PLAA Polyclonal Antibody (ARO-A13590) is a rabbit polyclonal antibody detecting PLAP, PLA2P, Phospholipase A-2-activating protein, PLAA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human PLAA (Glu162-Ala312). |
| 靶标 | PLAP, PLA2P, Phospholipase A-2-activating protein, PLAA |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9Y263 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Phospholipase A-2-activating protein (PLAA) is a ~87 kDa protein. Plays a role in protein ubiquitination, sorting and degradation through its association with VCP. Involved in ubiquitin-mediated membrane proteins trafficking to late endosomes in an ESCRT-dependent manner, and hence plays a role in synaptic vesicle recycling. May play a role in macroautophagy, regulating for instance the clearance of damaged lysosomes. Plays a role in cerebellar Purkinje cell development. Positively regulates cytosolic and calcium-independent phospholipase A2 activities in a tumor necrosis factor alpha (TNF)- or lipopolysaccharide (LPS)-dependent manner, and hence prostaglandin E2 biosynthesis. 1. Papadopoulos, C. et al. (2017) The EMBO journal 36, 135-150. PMID: 27753622 2. Zhang, F. et al. (2008) Cellular signalling 20, 844-61. PMID: 18291623 3. Falik Zaccai, TC. et al. (2017) Brain : a journal of neurology 140, 370-386. PMID: 28007986 |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理