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Anti-SIAE Polyclonal Antibody (ARO-A13642)

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概述
货号ARO-A13642
品牌ProteoGenix
描述
Anti-SIAE Polyclonal Antibody (ARO-A13642) is a rabbit polyclonal antibody detecting YSG2, H-Lse, Sialic acid-specific 9-O-acetylesterase, Sialate O-acetylesterase, SIAE in ELISA, IHC, WB. Suitable for Human, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SIAE (Ala22-Pro244).
靶标YSG2, H-Lse, Sialic acid-specific 9-O-acetylesterase, Sialate O-acetylesterase, SIAE
纯化方式Purified by antigen affinity column.
Accession号Q9HAT2
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sialate O-acetylesterase (SIAE) is a ~58 kDa protein. Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity.

1. Mandal, C. et al. (2012) Glycobiology 22, 70-83. PMID: 21803834
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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