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Anti-NEIL1 Polyclonal Antibody (ARO-A13686)

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概述
货号ARO-A13686
品牌ProteoGenix
描述
Anti-NEIL1 Polyclonal Antibody (ARO-A13686) is a rabbit polyclonal antibody detecting Endonuclease 8-like 1, DNA glycosylase/AP lyase Neil1, Endonuclease VIII-like 1, Nei-like protein 1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Nei homolog 1, NEIL1, FPG1, NEH1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human NEIL1 (Ser43-Ala314).
靶标Endonuclease 8-like 1, DNA glycosylase/AP lyase Neil1, Endonuclease VIII-like 1, Nei-like protein 1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Nei homolog 1, NEIL1, FPG1, NEH1
纯化方式Purified by antigen affinity column.
Accession号Q96FI4
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Endonuclease 8-like 1 (NEIL1) is a ~43 kDa protein. Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as a DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-NEIL1 Polyclonal Antibody

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