

| 货号 | ARO-A13670 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-HEPH Polyclonal Antibody (ARO-A13670) is a rabbit polyclonal antibody detecting HEPH, KIAA0698, Hephaestin in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human HEPH (Ala24-Cys366). |
| 靶标 | HEPH, KIAA0698, Hephaestin |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9BQS7 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Hephaestin is a ~130 kDa protein. Plasma membrane ferroxidase that mediates the extracellular conversion of ferrous/Fe(2+) iron into its ferric/Fe(3+) form. Couples ferroportin which specifically exports ferrous/Fe(2+) iron from cells to transferrin that only binds and shuttles extracellular ferric/Fe(3+) iron throughout the body. By helping iron transfer from cells to blood mainly contributes to dietary iron absorption by the intestinal epithelium and more generally regulates iron levels in the body. 1. Vashchenko, G. et al. (2012) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 17, 1187-95. PMID: 22961397 2. Baringer, SL. et al. (2023) Journal of biomedical science 30, 36. PMID: 37277838 |
| Note | For research use only. |

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