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Anti-PIK3AP1 Polyclonal Antibody (ARO-A13745)

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概述
货号ARO-A13745
品牌ProteoGenix
描述
Anti-PIK3AP1 Polyclonal Antibody (ARO-A13745) is a rabbit polyclonal antibody detecting BCAP, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, B-cell adapter for phosphoinositide 3-kinase, Phosphoinositide 3-kinase adapter protein 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human PIK3AP1 (Leu489-Ser730).
靶标BCAP, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, B-cell adapter for phosphoinositide 3-kinase, Phosphoinositide 3-kinase adapter protein 1
纯化方式Purified by antigen affinity column.
Accession号Q6ZUJ8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1) is a ~90 kDa protein. Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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