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Anti-MPP5 Polyclonal Antibody (ARO-A13725)

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概述
货号ARO-A13725
品牌ProteoGenix
描述
Anti-MPP5 Polyclonal Antibody (ARO-A13725) is a rabbit polyclonal antibody detecting PALS1, MAGUK p55 subfamily member 5, MPP5 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Dog, Rat, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human MPP5 (Asn455-Arg675).
靶标PALS1, MAGUK p55 subfamily member 5, MPP5
纯化方式Purified by antigen affinity column.
Accession号Q8N3R9
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein PALS1 (MPP5) is a ~77 kDa protein. Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface. Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity. Required during embryonic and postnatal retinal development. Required for the maintenance of cerebellar progenitor cells in an undifferentiated proliferative state, preventing premature differentiation, and is required for cerebellar histogenesis, fissure formation, cerebellar layer organization and cortical development.

1. Wells, CD. et al. (2006) Cell 125, 535-48. PMID: 16678097
2. Li, Y. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 17444-9. PMID: 25385611
3. Brinkmann, BF. et al. (2016) Molecular biology of the cell 27, 2811-21. PMID: 27466317
4. Carvalho, G. et al. (2011) PloS one 6, e18159. PMID: 21479189
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-MPP5 Polyclonal Antibody

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