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Anti-PLA1A Polyclonal Antibody (ARO-A13759)

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概述
货号ARO-A13759
品牌ProteoGenix
描述
Anti-PLA1A Polyclonal Antibody (ARO-A13759) is a rabbit polyclonal antibody detecting PSPLA1, PS-PLA1, Phosphatidylserine-specific phospholipase A1, PLA1A, NMD, Phospholipase A1 member A in ELISA, IHC, WB. Suitable for Human, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human PLA1A (Leu309-Lys452).
靶标PSPLA1, PS-PLA1, Phosphatidylserine-specific phospholipase A1, PLA1A, NMD, Phospholipase A1 member A
纯化方式Purified by antigen affinity column.
Accession号Q53H76
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Phospholipase A1 member A (PLA1A) is a ~49 kDa protein. Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein.

1. Nagai, Y. et al. (1999) The Journal of biological chemistry 274, 11053-9. PMID: 10196188
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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