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Anti-DUSP6 Polyclonal Antibody (ARO-A13768)

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概述
货号ARO-A13768
品牌ProteoGenix
描述
Anti-DUSP6 Polyclonal Antibody (ARO-A13768) is a rabbit polyclonal antibody detecting Mitogen-activated protein kinase phosphatase 3, MKP3, DUSP6, PYST1, MAP kinase phosphatase 3, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, MKP-3 in ELISA, IHC, WB. Suitable for Bos taurus, Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Bos taurus, Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human DUSP6 (Met1-Leu347).
靶标Mitogen-activated protein kinase phosphatase 3, MKP3, DUSP6, PYST1, MAP kinase phosphatase 3, Dual specificity protein phosphatase PYST1, Dual specificity protein phosphatase 6, MKP-3
纯化方式Purified by antigen affinity column.
Accession号Q16828
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Dual specificity protein phosphatase 6 (DUSP6) is a ~42 kDa protein. Dual specificity protein phosphatase, which mediates dephosphorylation and inactivation of MAP kinases. Has a specificity for the ERK family. Plays an important role in alleviating chronic postoperative pain. Necessary for the normal dephosphorylation of the long-lasting phosphorylated forms of spinal MAPK1/3 and MAP kinase p38 induced by peripheral surgery, which drives the resolution of acute postoperative allodynia. Also important for dephosphorylation of MAPK1/3 in local wound tissue, which further contributes to resolution of acute pain.

1. Groom, LA. et al. (1996) The EMBO journal 15, 3621-32. PMID: 8670865
2. Mishra, A. et al. (2017) eLife 6. PMID: 29043977
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-DUSP6 Polyclonal Antibody

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