

| 货号 | ARO-A13778 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-TAF12 Polyclonal Antibody (ARO-A13778) is a rabbit polyclonal antibody detecting TAF2J, Transcription initiation factor TFIID subunit 12, TAFII20, TAFII20/TAFII15, TAF15, TAF12, TAFII-20/TAFII-15, Transcription initiation factor TFIID 20/15 kDa subunits in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus.
Highlights
|
| 种属反应性 | Human, Mouse, Bos taurus |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human TAF12 (Met1-Lys161). |
| 靶标 | TAF2J, Transcription initiation factor TFIID subunit 12, TAFII20, TAFII20/TAFII15, TAF15, TAF12, TAFII-20/TAFII-15, Transcription initiation factor TFIID 20/15 kDa subunits |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q16514 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Transcription initiation factor TFIID subunit 12 (TAF12) is a ~17 kDa protein. The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription. TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC). The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13. Component of the TATA-binding protein-free TAF complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. 1. Chen, X. et al. (2021) Science (New York, N.Y.) 372. PMID: 33795473 2. Brand, M. et al. (1999) The Journal of biological chemistry 274, 18285-9. PMID: 10373431 3. Mengus, G. et al. (1995) The EMBO journal 14, 1520-31. PMID: 7729427 4. Hoffmann, A. et al. (1996) Nature 380, 356-9. PMID: 8598932 5. Hoffmann, A. et al. (1996) The Journal of biological chemistry 271, 18194-202. PMID: 8663456 6. Ogryzko, VV. et al. (1998) Cell 94, 35-44. PMID: 9674425 7. Vassilev, A. et al. (1998) Molecular cell 2, 869-75. PMID: 9885574 |
| Note | For research use only. |

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