

| 货号 | ARO-A13807 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-TFDP1 Polyclonal Antibody (ARO-A13807) is a rabbit polyclonal antibody detecting DRTF1-polypeptide 1, DRTF1, E2F dimerization partner 1, TFDP1, DP1, Transcription factor Dp-1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus.
Highlights
|
| 种属反应性 | Human, Mouse, Bos taurus |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human TFDP1 (Gly6-Asp410). |
| 靶标 | DRTF1-polypeptide 1, DRTF1, E2F dimerization partner 1, TFDP1, DP1, Transcription factor Dp-1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q14186 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Transcription factor Dp-1 (TFDP1) is a ~45 kDa protein. Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters. 1. Wu, CL. et al. (1995) Molecular and cellular biology 15, 2536-46. PMID: 7739537 2. Helin, K. et al. (1993) Genes & development 7, 1850-61. PMID: 8405995 3. Zaragoza, K. et al. (2010) Molecular and cellular biology 30, 2293-304. PMID: 20176812 |
| Note | For research use only. |

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