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Anti-VLDLR Polyclonal Antibody (ARO-A13866)

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概述
货号ARO-A13866
品牌ProteoGenix
描述
Anti-VLDLR Polyclonal Antibody (ARO-A13866) is a rabbit polyclonal antibody detecting Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR in ELISA, IHC, WB. Suitable for Chicken, Human, Mouse, Oryctolagus cuniculus, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Chicken, Human, Mouse, Oryctolagus cuniculus, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human VLDLR (Lys418-Ala722).
靶标Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR
纯化方式Purified by antigen affinity column.
Accession号P98155
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Very low-density lipoprotein receptor (VLDLR) is a ~96 kDa protein. Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism. Also binds to a wide range of other molecules including Reelin/RELN or apolipoprotein E/APOE-containing ligands as well as clusterin/CLU. In the off-state of the pathway, forms homooligomers or heterooligomers with LRP8. Upon binding to ligands, homooligomers are rearranged to higher order receptor clusters that transmit the extracellular RELN signal to intracellular signaling processes by binding to DAB1. This interaction results in phosphorylation of DAB1 leading to the ultimate cell responses required for the correct positioning of newly generated neurons.

1. Leeb, C. et al. (2014) The Journal of biological chemistry 289, 4161-72. PMID: 24381170
2. Dlugosz, P. et al. (2019) Frontiers in molecular neuroscience 12, 53. PMID: 30873003
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-VLDLR Polyclonal Antibody

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