

| 货号 | ARO-A13860 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-RELB Polyclonal Antibody (ARO-A13860) is a rabbit polyclonal antibody detecting RELB, Transcription factor RelB, I-Rel in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
|
| 种属反应性 | Human, Mouse |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human RELB (Asp248-Asp492). |
| 靶标 | RELB, Transcription factor RelB, I-Rel |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q01201 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Transcription factor RelB is a ~62 kDa protein. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. 1. Sharfe, N. et al. (2015) Journal of autoimmunity 65, 90-100. PMID: 26385063 |
| Note | For research use only. |

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