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Anti-CXADR Polyclonal Antibody (ARO-A13876)

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概述
货号ARO-A13876
品牌ProteoGenix
描述
Anti-CXADR Polyclonal Antibody (ARO-A13876) is a rabbit polyclonal antibody detecting Coxsackievirus B-adenovirus receptor, CVB3-binding protein, Coxsackievirus and adenovirus receptor, HCVADR, CXADR, hCAR, CAR in ELISA, IHC, WB. Suitable for Mouse, Rat, Bos taurus, Human, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Mouse, Rat, Bos taurus, Human, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CXADR (Leu20-Val229).
靶标Coxsackievirus B-adenovirus receptor, CVB3-binding protein, Coxsackievirus and adenovirus receptor, HCVADR, CXADR, hCAR, CAR
纯化方式Purified by antigen affinity column.
Accession号P78310
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Coxsackievirus and adenovirus receptor (CXADR) is a ~40 kDa protein. Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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