Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景
Neutrophil defensin 3 (DEFA3) is a ~10 kDa protein. Effector molecule of the innate immune system that acts via antibiotic-like properties against a broad array of infectious agents including bacteria, fungi, and viruses. Possesses the ability to neutralize bacterial toxins such as B.anthracis lethal factor, Clostridium difficile cytotoxin B as well as leukocidin produced by Staphylococcus aureus. Also blocks herpes simplex virus infection by interacting with envelope glycoprotein B and thus preventing its binding to heparan sulfate, the receptor for attachment.
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2. Kim, C. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 4830-5. PMID: 15772169
3. Hazrati, E. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 177, 8658-66. PMID: 17142766
4. Giesemann, T. et al. (2008) Gastroenterology 134, 2049-58. PMID: 18435932
5. Cardot-Martin, E. et al. (2015) Letters in applied microbiology 61, 158-64. PMID: 25963798
