

| 货号 | ARO-A13940 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-EMD Polyclonal Antibody (ARO-A13940) is a rabbit polyclonal antibody detecting EMD, EDMD, STA, Emerin in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human EMD (Ser66-Asn252). |
| 靶标 | EMD, EDMD, STA, Emerin |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P50402 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Emerin (EMD) is a ~28 kDa protein. Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. 1. Tsatskis, Y. et al. (2020) Science advances 6, eabb4591. PMID: 32923640 |
| Note | For research use only. |

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