

| 货号 | ARO-A14077 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-AOC1/DAO Polyclonal Antibody (ARO-A14077) is a rabbit polyclonal antibody detecting AOC1, ABP1, DAO, Kidney amine oxidase, Histaminase, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein 1, Diamine oxidase, KAO, DAO1, Amine oxidase copper domain-containing protein 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human AOC1/DAO (Glu20-Trp322). |
| 靶标 | AOC1, ABP1, DAO, Kidney amine oxidase, Histaminase, Amiloride-sensitive amine oxidase [copper-containing], Amiloride-binding protein 1, Diamine oxidase, KAO, DAO1, Amine oxidase copper domain-containing protein 1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P19801 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Diamine oxidase [copper-containing] (AOC1/DAO) is a ~85 kDa protein. Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes. 1. Elmore, BO. et al. (2002) Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 7, 565-79. PMID: 12072962 2. McGrath, AP. et al. (2009) Biochemistry 48, 9810-22. PMID: 19764817 3. Hölttä, E. et al. (1975) The Biochemical journal 145, 373-8. PMID: 239684 4. Novotny, WF. et al. (1994) The Journal of biological chemistry 269, 9921-5. PMID: 8144586 |
| Note | For research use only. |

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