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Anti-FBP1 Polyclonal Antibody (ARO-A14163)

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概述
货号ARO-A14163
品牌ProteoGenix
描述
Anti-FBP1 Polyclonal Antibody (ARO-A14163) is a rabbit polyclonal antibody detecting FBPase 1, FBP1, Liver FBPase, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, FBP, Fructose-1, 6-bisphosphatase 1 in ELISA, IHC, WB. Suitable for Human, Bos taurus, Oryctolagus cuniculus, Ovis aries, Pig.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Bos taurus, Oryctolagus cuniculus, Ovis aries, Pig
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human FBP1 (Met1-Gln338).
靶标FBPase 1, FBP1, Liver FBPase, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, FBP, Fructose-1, 6-bisphosphatase 1
纯化方式Purified by antigen affinity column.
Accession号P09467
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Fructose-1,6-bisphosphatase 1 (FBP1) is a ~36 kDa protein. Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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