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Anti-RALA Polyclonal Antibody (ARO-A14142)

概述
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参考文献

概述

货号	ARO-A14142
品牌	ProteoGenix
描述	Anti-RALA Polyclonal Antibody (ARO-A14142) is a rabbit polyclonal antibody detecting Ras-related protein Ral-A, RAL, RALA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Saguinus oedipus. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat, Saguinus oedipus
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human RALA (Met1-Leu206).
靶标	Ras-related protein Ral-A, RAL, RALA
纯化方式	Purified by antigen affinity column.
Accession号	P11233
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Ras-related protein Ral-A (RALA) is a ~23 kDa protein. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. 1. Cascone, I. et al. (2008) The EMBO journal 27, 2375-87. PMID: 18756269 2. Aziziyeh, AI. et al. (2009) Cellular signalling 21, 1207-17. PMID: 19306925 3. Balasubramanian, N. et al. (2010) Current biology : CB 20, 75-9. PMID: 20005108 4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277 5. Hiatt, SM. et al. (2018) PLoS genetics 14, e1007671. PMID: 30500825
Note	For research use only.

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公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-RALA Polyclonal Antibody

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