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Anti-S100B Polyclonal Antibody (ARO-A14226)

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概述
货号ARO-A14226
品牌ProteoGenix
描述
Anti-S100B Polyclonal Antibody (ARO-A14226) is a rabbit polyclonal antibody detecting S100 calcium-binding protein B, S100B, S-100 protein subunit beta, Protein S100-B, S-100 protein beta chain in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Oryctolagus cuniculus.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus, Oryctolagus cuniculus
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human S100B (Met1-Glu92).
靶标S100 calcium-binding protein B, S100B, S-100 protein subunit beta, Protein S100-B, S-100 protein beta chain
纯化方式Purified by antigen affinity column.
Accession号P04271
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein S100-B (S100B) is a ~10 kDa protein. Small zinc- and- and calcium-binding protein that is highly expressed in astrocytes and constitutes one of the most abundant soluble proteins in brain. Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Acts as a neurotrophic factor that promotes astrocytosis and axonal proliferation. Involved in innervation of thermogenic adipose tissue by acting as an adipocyte-derived neurotrophic factor that promotes sympathetic innervation of adipose tissue.

1. Ostendorp, T. et al. (2011) Biochimica et biophysica acta 1813, 1083-91. PMID: 20950652
2. Baudier, J. et al. (1984) Biochimica et biophysica acta 790, 164-73. PMID: 6487634
3. Gilquin, B. et al. (2010) Molecular and cellular biology 30, 2724-36. PMID: 20351179
4. Yamaguchi, F. et al. (2012) The Journal of biological chemistry 287, 13787-98. PMID: 22399290
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-S100B Polyclonal Antibody

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