

| 货号 | ARO-A14240 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-FN1 Polyclonal Antibody (ARO-A14240) is a rabbit polyclonal antibody detecting Cold-insoluble globulin, CIG, FN, Fibronectin, FN1 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, Bos taurus, Equus caballus, Chicken, Notophthalmus viridescens, Oryctolagus cuniculus.
Highlights
|
| 种属反应性 | Human, Mouse, Dog, Rat, Bos taurus, Equus caballus, Chicken, Notophthalmus viridescens, Oryctolagus cuniculus |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human FN1 (Gly313-Ser607). |
| 靶标 | Cold-insoluble globulin, CIG, FN, Fibronectin, FN1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P02751 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Fibronectin (FN) is a ~272 kDa protein. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. Acts as a ligand for the LILRB4 receptor, inhibiting FCGR1A/CD64-mediated monocyte activation. 1. Owens, RJ. et al. (1986) The EMBO journal 5, 2825-30. PMID: 3024962 2. Garcia-Pardo, A. et al. (1987) The Biochemical journal 241, 923-8. PMID: 3593230 3. Calaycay, J. et al. (1985) The Journal of biological chemistry 260, 12136-41. PMID: 3900070 4. Rostagno, A. et al. (1994) The Journal of biological chemistry 269, 31938-45. PMID: 7989369 5. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617 |
| Note | For research use only. |

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