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Anti-LYPLA2 Polyclonal Antibody (ARO-A14292)

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概述
货号ARO-A14292
品牌ProteoGenix
描述
Anti-LYPLA2 Polyclonal Antibody (ARO-A14292) is a rabbit polyclonal antibody detecting LYPLA2, APT-2, LysoPLA II, LPL-II, Acyl-protein thioesterase 2, Lysophospholipase II, APT2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human LYPLA2 (Met1-Thr196).
靶标LYPLA2, APT-2, LysoPLA II, LPL-II, Acyl-protein thioesterase 2, Lysophospholipase II, APT2
纯化方式Purified by antigen affinity column.
Accession号O95372
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Acyl-protein thioesterase 2 (LYPLA2) is a ~24 kDa protein. Acts as an acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GSDMD, GAP43, ZDHHC6 or HRAS. Deacylates GAP43. Mediates depalmitoylation of ZDHHC6. Has lysophospholipase activity. Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G) > prostaglandin E2 glycerol ester (PGE2-G) > prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G).

1. Tomatis, VM. et al. (2010) PloS one 5, e15045. PMID: 21152083
2. Abrami, L. et al. (2017) eLife 6. PMID: 28826475
3. Manna, JD. et al. (2014) The Journal of biological chemistry 289, 33741-53. PMID: 25301951
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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