

| 货号 | ARO-A14305 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-STAM2 Polyclonal Antibody (ARO-A14305) is a rabbit polyclonal antibody detecting STAM2, Signal transducing adapter molecule 2, Hrs-binding protein, STAM-2, HBP in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human STAM2 (Met1-Leu377). |
| 靶标 | STAM2, Signal transducing adapter molecule 2, Hrs-binding protein, STAM-2, HBP |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | O75886 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Signal transducing adapter molecule 2 (STAM2) is a ~58 kDa protein. Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as a sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. |
| Note | For research use only. |

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