

| 货号 | ARO-A14354 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-APAF1 Polyclonal Antibody (ARO-A14354) is a rabbit polyclonal antibody detecting APAF1, APAF-1, Apoptotic protease-activating factor 1, KIAA0413 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human APAF1 (Ser31-Phe350). |
| 靶标 | APAF1, APAF-1, Apoptotic protease-activating factor 1, KIAA0413 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | O14727 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Apoptotic protease-activating factor 1 (APAF1) is a ~141 kDa protein. Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis. |
| Note | For research use only. |

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