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Anti-AKR1B10 Polyclonal Antibody (ARO-A14330)

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概述
货号ARO-A14330
品牌ProteoGenix
描述
Anti-AKR1B10 Polyclonal Antibody (ARO-A14330) is a rabbit polyclonal antibody detecting SI reductase, ARP, Small intestine reductase, ARL-1, Aldose reductase-related protein, Aldose reductase-like, AKR1B11, Aldo-keto reductase family 1 member B10, hARP, AKR1B10 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human AKR1B10 (Met1-Tyr316).
靶标SI reductase, ARP, Small intestine reductase, ARL-1, Aldose reductase-related protein, Aldose reductase-like, AKR1B11, Aldo-keto reductase family 1 member B10, hARP, AKR1B10
纯化方式Purified by antigen affinity column.
Accession号O60218
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Aldo-keto reductase family 1 member B10 (AKR1B10) is a ~36 kDa protein. Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays strong enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal. Plays a critical role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls). Displays no reductase activity towards glucose.

1. Crosas, B. et al. (2003) The Biochemical journal 373, 973-9. PMID: 12732097
2. Gallego, O. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 20764-9. PMID: 18087047
3. Martin, HJ. et al. (2009) Chemico-biological interactions 178, 145-50. PMID: 19013440
4. Zhong, L. et al. (2009) Biochemical and biophysical research communications 387, 245-50. PMID: 19563777
5. Cao, D. et al. (1998) The Journal of biological chemistry 273, 11429-35. PMID: 9565553
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-AKR1B10 Polyclonal Antibody

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