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Anti-DIAPH1 Polyclonal Antibody (ARO-A14324)

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概述
货号ARO-A14324
品牌ProteoGenix
描述
Anti-DIAPH1 Polyclonal Antibody (ARO-A14324) is a rabbit polyclonal antibody detecting Protein diaphanous homolog 1, DIAP1, DRF1, Diaphanous-related formin-1, DIAPH1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human DIAPH1 (Asp389-Pro583).
靶标Protein diaphanous homolog 1, DIAP1, DRF1, Diaphanous-related formin-1, DIAPH1
纯化方式Purified by antigen affinity column.
Accession号O60610
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein diaphanous homolog 1 (DIAPH1) is a ~141 kDa protein. Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration.

1. Zaoui, K. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 18517-22. PMID: 20937854
2. Bai, SW. et al. (2011) BMC biology 9, 54. PMID: 21834987
3. Stritt, S. et al. (2016) Blood 127, 2903-14. PMID: 26912466
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-DIAPH1 Polyclonal Antibody

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