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Anti-SPRY2 Polyclonal Antibody (ARO-A14334)

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概述
货号ARO-A14334
品牌ProteoGenix
描述
Anti-SPRY2 Polyclonal Antibody (ARO-A14334) is a rabbit polyclonal antibody detecting Spry-2, SPRY2, Protein sprouty homolog 2 in ELISA, IHC, WB. Suitable for Human, Mouse, Bos taurus, Chlorocebus aethiops, Chicken, Macaca fascicularis, Pongo abelii.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Bos taurus, Chlorocebus aethiops, Chicken, Macaca fascicularis, Pongo abelii
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SPRY2 (Ser116-Thr305).
靶标Spry-2, SPRY2, Protein sprouty homolog 2
纯化方式Purified by antigen affinity column.
Accession号O43597
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Protein sprouty homolog 2 (SPRY2) is a ~34 kDa protein. Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2. Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis. Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells. Inhibits CBL/C-CBL-mediated EGFR ubiquitination.

1. Chandramouli, S. et al. (2008) The Journal of biological chemistry 283, 1679-1691. PMID: 17974561
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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