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Anti-HMGB3 Polyclonal Antibody (ARO-A14342)

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概述
货号ARO-A14342
品牌ProteoGenix
描述
Anti-HMGB3 Polyclonal Antibody (ARO-A14342) is a rabbit polyclonal antibody detecting HMG-4, High mobility group protein 2a, HMG2A, HMG4, HMGB3, High mobility group protein 4, High mobility group protein B3, HMG-2a in ELISA, IHC, WB. Suitable for Mouse, Bos taurus, Chicken, Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Mouse, Bos taurus, Chicken, Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human HMGB3 (Ser14-Ala176).
靶标HMG-4, High mobility group protein 2a, HMG2A, HMG4, HMGB3, High mobility group protein 4, High mobility group protein B3, HMG-2a
纯化方式Purified by antigen affinity column.
Accession号O15347
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

High mobility group protein B3 (HMGB3) is a ~22 kDa protein. Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner. Associates with chromatin and binds DNA with a preference for non-canonical DNA structures such as single-stranded DNA. Can bend DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor.

NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-HMGB3 Polyclonal Antibody

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