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Anti-CLIC1 Polyclonal Antibody (ARO-A14369)

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概述
货号ARO-A14369
品牌ProteoGenix
描述
Anti-CLIC1 Polyclonal Antibody (ARO-A14369) is a rabbit polyclonal antibody detecting Regulatory nuclear chloride ion channel protein, CLIC1, NCC27, Nuclear chloride ion channel 27, Chloride channel ABP, Chloride intracellular channel protein 1, hRNCC, G6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bos taurus, Oryctolagus cuniculus, Pig.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat, Bos taurus, Oryctolagus cuniculus, Pig
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CLIC1 (Lys79-Lys241).
靶标Regulatory nuclear chloride ion channel protein, CLIC1, NCC27, Nuclear chloride ion channel 27, Chloride channel ABP, Chloride intracellular channel protein 1, hRNCC, G6
纯化方式Purified by antigen affinity column.
Accession号O00299
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Chloride intracellular channel protein 1 (CLIC1) is a ~26 kDa protein. In the soluble state, catalyzes glutaredoxin-like thiol disulfide exchange reactions with reduced glutathione as electron donor. Reduces selenite and dehydroascorbate and may act as an antioxidant during oxidative stress response. Can insert into membranes and form voltage-dependent multi-ion conductive channels. Membrane insertion seems to be redox-regulated and may occur only under oxidizing conditions. Involved in regulation of the cell cycle.

1. Al Khamici, H. et al. (2015) PloS one 10, e115699. PMID: 25581026
2. Alghalayini, A. et al. (2023) Biomolecules 13. PMID: 37759794
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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