Anti-Human/Mouse/Rat GPX4 Monoclonal Antibody (1A725) (HW551015)

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概述

货号	HW551015
品牌	abinScience
描述	Anti-Human/Mouse/Rat GPX4 Monoclonal Antibody (1A725) (HW551015) is a mouse monoclonal antibody detecting GPX4. Suitable for Human, Mouse, and Rat. Highlights ●Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat
应用	ELISA, WB
宿主	Mouse
克隆类型	Monoclonal
同种型	IgG2b
克隆号	1A725
免疫原	E. coli - derived recombinant rat GPX4 (Gly73-Leu196).
靶标	EC:1.11.1.12, EC:1.11.1.9, GPX4, GPx-4, GSHPx-4, Glutathione peroxidase 4, PHGPx, Phospholipid hydroperoxide glutathione peroxidase GPX4
内毒素水平	Please contact with the lab for this information.
观测分子量	20 kDa
纯化方式	Protein A/G purified from cell culture supernatant.
Accession号	P36970
状态	Liquid
保存溶液	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Phospholipid hydroperoxide glutathione peroxidase (GPX4) is a ~22 kDa protein. Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins. Can also reduce fatty acid hydroperoxide, cholesterol hydroperoxide and thymine hydroperoxide. Plays a key role in protecting cells from oxidative damage by preventing membrane lipid peroxidation. Required to prevent cells from ferroptosis, a non-apoptotic cell death resulting from an iron-dependent accumulation of lipid reactive oxygen species. The presence of selenocysteine (Sec) versus Cys at the active site is essential for life: it provides resistance to overoxidation and prevents cells against ferroptosis. 1. Roveri, A. et al. (1992) The Journal of biological chemistry 267, 6142-6. PMID: 1556123 2. Arai, M. et al. (1999) The Journal of biological chemistry 274, 4924-33. PMID: 9988735
Note	For research use only

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参考文献

产品说明书

Anti-Human/Mouse/Rat GPX4 Monoclonal Antibody (1A725).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

Anti-Human/Mouse/Rat GPX4 Monoclonal Antibody (1A725) (HW551015)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human/Mouse/Rat GPX4 Monoclonal Antibody (1A725) (HW551015)

概述

图片

参考文献

产品说明书

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