Anti-Mouse IL-5 Polyclonal Antibody (MY218014)

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概述
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参考文献
产品说明书

概述

货号

MY218014

品牌

abinScience

描述

Anti-Mouse IL5 Polyclonal Antibody (MY218014) is a rabbit polyclonal antibody detecting Il5. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

同种型

IgG

克隆类型

Polyclonal

免疫原

E. coli - derived recombinant Mouse IL5 (Met21-Gly133).

靶标

B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, IL-5, Il-5, Il5, Interleukin-5, T-cell replacing factor, TRF

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P04401

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Interleukin-5 (IL5) is a ~15 kDa protein. Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. IL5 is the therapeutic target of mepolizumab (Nucala).

1. Vallance, BA. et al. (1999) The American journal of physiology 277, G400-8. PMID: 10444455

2. Barry, SC. et al. (1991) Cytokine 3, 339-44. PMID: 1873482

3. Karasuyama, H. et al. (1988) The Journal of experimental medicine 167, 1377-90. PMID: 3128631

Note

For research use only

图片

参考文献

产品说明书

Anti-Mouse IL-5 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse IL-5 Polyclonal Antibody (MY218014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse IL-5 Polyclonal Antibody (MY218014)

概述

图片

参考文献

产品说明书

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