

| 货号 | VK727044 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-TGEV RBD Polyclonal Antibody (VK727044) is a rabbit polyclonal antibody detecting TGEV RBD. Suitable for Porcine transmissible gastroenteritis coronavirus, Feline coronavirus, and Porcine respiratory coronavirus.
Highlights
| ||||||||
| 种属反应性 | Porcine transmissible gastroenteritis coronavirus (TGEV), Feline coronavirus (FCoV) | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant TGEV RBD (Pro521-Pro667). | ||||||||
| 靶标 | E2, Peplomer protein, S, S glycoprotein, Spike glycoprotein | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | P07946 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 背景 | Spike glycoprotein (RBD) is a ~160 kDa protein. S1 region attaches the virion to the cell membrane by interacting with host ANPEP/aminopeptidase N, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. | ||||||||
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理