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Anti-HBoV1 Minor capsid protein VP1 Polyclonal Antibody (VK140014)

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概述
货号VK140014
品牌abinScience
描述
Anti-HBoV1 Minor capsid protein VP1 Polyclonal Antibody (VK140014) is a rabbit polyclonal antibody detecting Minor capsid protein VP1. Suitable for Primate bocaparvovirus 1.
种属反应性Primate bocaparvovirus 1 (Human bocavirus 1 type 1) (HBoV1)
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant HBoV1 Minor capsid protein VP1 (Lys181-Gly290).
靶标EC:3.1.1.4, Minor capsid protein VP1, VP1
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q3YPH4
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Minor capsid protein VP1 is a ~75 kDa protein. Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1 (Probable). The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid. The capsid encapsulates the genomic ssDNA (Probable). Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus.

1. Mietzsch, M. et al. (2017) Journal of virology 91. PMID: 28331084
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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