Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

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规格：

50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HD636014

品牌

abinScience

描述

Anti-Human SLC39A7 Polyclonal Antibody (HD636014) is a rabbit polyclonal antibody detecting SLC39A7. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human SLC39A7 (Gly30-Thr133).

靶标

HKE4, Histidine-rich membrane protein Ke4, RING5, Really interesting new gene 5 protein, SLC39A7, Solute carrier family 39 member 7, ZIP7, Zinc transporter SLC39A7, Zrt-, Irt-like protein 7

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q92504

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Zinc transporter SLC39A7 is a ~50 kDa protein. Transports Zn(2+) from the endoplasmic reticulum (ER)/Golgi apparatus to the cytosol, playing an essential role in the regulation of cytosolic zinc levels. Acts as a gatekeeper of zinc release from intracellular stores, requiring post-translational activation by phosphorylation, resulting in activation of multiple downstream pathways leading to cell growth and proliferation. Has an essential role in B cell development and is required for proper B cell receptor signaling. Plays an important role in maintaining intestinal epithelial homeostasis and skin dermis development by regulating ER function. Controls cell signaling pathways involved in glucose metabolism in skeletal muscle.

1. Taylor, KM. et al. (2004) The Biochemical journal 377, 131-9. PMID: 14525538

2. Huang, L. et al. (2005) The Journal of biological chemistry 280, 15456-63. PMID: 15705588

3. Nimmanon, T. et al. (2017) Metallomics : integrated biometal science 9, 471-481. PMID: 28205653

4. Woodruff, G. et al. (2018) Molecular pharmacology 94, 1092-1100. PMID: 29980658

5. Taylor, KM. et al. (2012) Science signaling 5, ra11. PMID: 22317921

6. Anzilotti, C. et al. (2019) Nature immunology 20, 350-361. PMID: 30718914

7. Fauster, A. et al. (2019) Cell death and differentiation 26, 1138-1155. PMID: 30237509

Note

For research use only

图片

参考文献

产品说明书

Anti-Human SLC39A7 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human SLC39A7 Polyclonal Antibody (HD636014)

概述

图片

参考文献

产品说明书

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