| 靶标 | 116 kDa U5 small nuclear ribonucleoprotein component, EFTUD2, Elongation factor Tu GTP-binding domain-containing protein 2, KIAA0031, SNRP116, SNU114 homolog, U5 snRNP-specific protein, 116 kDa, U5-116 kDa, hSNU114 |
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| 背景 | 116 kDa U5 small nuclear ribonucleoprotein component (EFTUD2) is a ~109 kDa protein. Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). 5. Zhan, X. et al. (2018) Science (New York, N.Y.) 359, 537-545. PMID: 293019619. Fica, SM. et al. (2019) Science (New York, N.Y.) 363, 710-714. PMID: 3070515410. Liu, S. et al. (2006) RNA (New York, N.Y.) 12, 1418-30. PMID: 16723661 |
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