Anti-Human PDE8A Polyclonal Antibody (HD652014)

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概述
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概述

货号

HD652014

品牌

abinScience

描述

Anti-Human PDE8A Polyclonal Antibody (HD652014) is a rabbit polyclonal antibody detecting PDE8A. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human PDE8A (Ser480-Glu829).

靶标

EC:3.1.4.53, High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A, PDE8A

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

O60658

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (PDE8A) is a ~93 kDa protein. Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development. Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling. Protects against cell death induced by hydrogen peroxide and staurosporine.

1. Wang, H. et al. (2008) Biochemistry 47, 12760-8. PMID: 18983167

2. Brown, KM. et al. (2013) Proceedings of the National Academy of Sciences of the United States of America 110, E1533-42. PMID: 23509299

Note

For research use only

图片

参考文献

产品说明书

Anti-Human PDE8A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PDE8A Polyclonal Antibody (HD652014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human PDE8A Polyclonal Antibody (HD652014)

概述

图片

参考文献

产品说明书

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