Anti-Human FMN2 Polyclonal Antibody (HD654014)

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概述
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参考文献
产品说明书

概述

货号

HD654014

品牌

abinScience

描述

Anti-Human FMN2 Polyclonal Antibody (HD654014) is a rabbit polyclonal antibody detecting FMN2. Suitable for Mouse and Human.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human FMN2 (Ser1361-Thr1722).

靶标

FMN2, Formin-2

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q9NZ56

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Formin-2 (FMN2) is a ~180 kDa protein. Actin-binding protein that is involved in actin cytoskeleton assembly and reorganization. Acts as an actin nucleation factor and promotes assembly of actin filaments together with SPIRE1 and SPIRE2. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning, asymmetric oocyte division and polar body extrusion during female germ cell meiosis. Plays a role in responses to DNA damage, cellular stress and hypoxia by protecting CDKN1A against degradation, and thereby plays a role in stress-induced cell cycle arrest.

1. Vizcarra, CL. et al. (2011) Proceedings of the National Academy of Sciences of the United States of America 108, 11884-9. PMID: 21730168

2. Peng, KW. et al. (2012) Biochimica et biophysica acta 1820, 469-81. PMID: 22330775

3. Yamada, K. et al. (2013) Molecular cell 49, 922-33. PMID: 23375502

4. Belin, BJ. et al. (2015) eLife 4, e07735. PMID: 26287480

Note

For research use only

图片

参考文献

产品说明书

Anti-Human FMN2 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FMN2 Polyclonal Antibody (HD654014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human FMN2 Polyclonal Antibody (HD654014)

概述

图片

参考文献

产品说明书

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