Anti-Human CRAT Polyclonal Antibody (HD657014)

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概述
图片
参考文献
产品说明书

概述

货号

HD657014

品牌

abinScience

描述

Anti-Human CRAT Polyclonal Antibody (HD657014) is a rabbit polyclonal antibody detecting CRAT. Suitable for Human, Rat, and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human CRAT (His31-Glu297).

靶标

CAT, CAT1, CRAT, Carnitine O-acetyltransferase, Carnitine acetylase, Carnitine acetyltransferase, CrAT, EC:2.3.1.137, EC:2.3.1.7

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

P43155

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

Carnitine O-acetyltransferase (CRAT) is a ~70 kDa protein. Catalyzes the reversible transfer of acyl groups from carnitine to coenzyme A (CoA) and regulates the acyl-CoA/CoA ratio. Also plays a crucial role in the transport of fatty acids for beta-oxidation. Responsible for the synthesis of short- and branched-chain acylcarnitines. Active towards some branched-chain amino acid oxidation pathway (BCAAO) intermediates. Trans-2-enoyl-CoAs and 2-methylacyl-CoAs are poor substrates.

1. Govindasamy, L. et al. (2004) Journal of structural biology 146, 416-24. PMID: 15099582

2. Drecourt, A. et al. (2018) American journal of human genetics 102, 266-277. PMID: 29395073

3. Violante, S. et al. (2013) Biochimica et biophysica acta 1832, 773-9. PMID: 23485643

Note

For research use only

图片

Western blot

Lane 1: Rat heart lysate
Lane 2: Rat skeletal muscle lysate

参考文献

产品说明书

Anti-Human CRAT Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CRAT Polyclonal Antibody (HD657014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CRAT Polyclonal Antibody (HD657014)

概述

图片

参考文献

产品说明书

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