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Anti-Human CEP63 Polyclonal Antibody (HD664014)

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概述
货号HD664014
品牌abinScience
描述
Anti-Human CEP63 Polyclonal Antibody (HD664014) is a rabbit polyclonal antibody detecting CEP63. Suitable for Human.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CEP63 (Met1-Ile309).
靶标CEP63, Centrosomal protein of 63 kDa, Cep63
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q96MT8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Centrosomal protein of 63 kDa (CEP63) is a ~81 kDa protein. Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned. Also recruits CDK1 to centrosomes. Plays a role in DNA damage response.

1. Löffler, H. et al. (2011) Cancer research 71, 2129-39. PMID: 21406398
2. Sir, JH. et al. (2011) Nature genetics 43, 1147-53. PMID: 21983783
3. Kodani, A. et al. (2015) eLife 4. PMID: 26297806
4. Kodani, A. et al. (2022) EMBO reports 23, e52211. PMID: 35793002
5. Ling, H. et al. (2022) Oncogene 41, 4433-4445. PMID: 35989368
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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