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Anti-Human ATXN7L3 Polyclonal Antibody (HD670014)

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规格:
  • 50ug
  • 100ug
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概述
货号HD670014
品牌abinScience
描述
Anti-Human ATXN7L3 Polyclonal Antibody (HD670014) is a rabbit polyclonal antibody detecting ATXN7L3. Suitable for Human and Mouse.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human ATXN7L3 (Asp54-Val247).
靶标ATXN7L3, Ataxin-7-like protein 3, SAGA-associated factor 11 homolog
内毒素水平Please contact with the lab for this information.
纯化方式Purified by antigen affinity column.
Accession号Q14CW9
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
背景

Ataxin-7-like protein 3 (ATXN7L3) is a ~38 kDa protein. Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex.

1. Zhao, Y. et al. (2008) Molecular cell 29, 92-101. PMID: 18206972
2. Lang, G. et al. (2011) Molecular and cellular biology 31, 3734-44. PMID: 21746879
3. Li, W. et al. (2016) Molecular and cellular biology 36, 2855-2866. PMID: 27601583
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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