Anti-Human ABRAXAS1 Polyclonal Antibody (HD497014)

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50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HD497014

品牌

abinScience

描述

Anti-Human ABRAXAS1 Polyclonal Antibody (HD497014) is a rabbit polyclonal antibody detecting ABRAXAS1. Suitable for Human.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human ABRAXAS1 (Met1-Ser174).

靶标

ABRA1, ABRAXAS1, BRCA1-A complex subunit Abraxas 1, CCDC98, Coiled-coil domain-containing protein 98, FAM175A, Protein FAM175A

内毒素水平

Please contact with the lab for this information.

纯化方式

Purified by antigen affinity column.

Accession号

Q6UWZ7

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

背景

BRCA1-A complex subunit Abraxas 1 (ABRAXAS1) is a ~46 kDa protein. Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Note

For research use only

图片

参考文献

产品说明书

Anti-Human ABRAXAS1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ABRAXAS1 Polyclonal Antibody (HD497014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human ABRAXAS1 Polyclonal Antibody (HD497014)

概述

图片

参考文献

产品说明书

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