

| 货号 | HD508014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human KIDINS220 Polyclonal Antibody (HD508014) is a rabbit polyclonal antibody detecting KIDINS220. Suitable for Rat and Human.
Highlights
| ||||||||
| 种属反应性 | Human, Rat | ||||||||
| 应用 | ELISA, IHC, WB | ||||||||
| 宿主 | Rabbit | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 同种型 | IgG | ||||||||
| 免疫原 | E. coli - derived recombinant Human KIDINS220 (Met1-Lys168). | ||||||||
| 靶标 | ARMS, Ankyrin repeat-rich membrane-spanning protein, KIAA1250, KIDINS220, Kinase D-interacting substrate of 220 kDa | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9ULH0 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
||||||||
| 产品使用信息 |
| ||||||||
| 背景 | Kinase D-interacting substrate of 220 kDa (KIDINS220) is a ~196 kDa protein. Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. | ||||||||
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理